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Jan 15, 2024 - Biotech and pharma companies are betting on a promising class of cancer drugs to drive growth

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TradeBriefs Editorial

From the Editor's Desk

Sentimentality and Being Mortal: Poet Mark Doty on the Passionate Fragility of Our Attachments

How beautiful and unbearable that only one of each exists — each lover, each child, each dog; that this particular chance-constellation of atoms has never before existed and will never again …Continued here

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Biotech and pharma companies are betting on a promising class of cancer drugs to drive growth    
Biotech and pharma companies are betting on a promising class of cancer drugs to drive growth
Pfizer believes the Seagen acquisition will bring in more than $10 billion in risk-adjusted sales by 2030. Seagen specifically brings four approved cancer drugs, including three ADCs, which will beef up Pfizer\'s own ADC portfolio. 


Work
Atlanta D.A. Defends Qualifications of Outside Lawyer She Hired for Trump Case    
Atlanta D.A. Defends Qualifications of Outside Lawyer She Hired for Trump Case
Instead, what Ms. Willis detailed were the frustrations and struggles that she said she has faced not only as a prosecutor, but also as a Black woman taking on the most powerful figure in the Republican Party.


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How, Where and When to Caucus in Iowa on Monday    
How, Where and When to Caucus in Iowa on Monday
After everyone has cast their secret ballots, workers at each caucus precinct will tally them up and report the total for each candidate to the state party. Results are typically available within a few hours.


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Joyce Randolph, Last of the ‘Honeymooners,’ Is Dead at 99    
Joyce Randolph, Last of the ‘Honeymooners,’ Is Dead at 99
Robert D. McFadden is a senior writer on the Obituaries desk and the winner of the 1996 Pulitzer Prize for spot news reporting. He joined The Times in May 1961 and is also the co-author of two books. More about Robert D. McFadden


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High School Principal Injured in Iowa School Shooting Has Died    
High School Principal Injured in Iowa School Shooting Has Died
In a statement posted on social media, the Perry Community School District described the principal as a “tremendous leader” and said, “Our school community is heartbroken by Dan’s death.”


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Dangerous Subzero Wind Chills Blanket Much of the U.S.    
Dangerous Subzero Wind Chills Blanket Much of the U.S.
An open-flame stove was being used to heat the R.V., and a tree fell on it, starting the fire. One woman in her early 30s was killed, while three other people in the recreational vehicle managed to escape.


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No. 4 UConn makes case for top team after win    
No. 4 UConn makes case for top team after win
\"He has the experience from last year coming off the bench,\" Hurley said. \"We\'ll do that initially with him and kind of play him like we did last year -- short spurts until he\'s potentially ready to do starter minutes.\"


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Scenes From a Harsh Winter Sweeping the U.S.    
Scenes From a Harsh Winter Sweeping the U.S.
Workers removed snow from Highmark Stadium in Orchard Park, N.Y., on Sunday. A potentially dangerous snowstorm that hit the Buffalo region on Saturday led the N.F.L. to push back the Bills wild-card playoff game against the Pittsburgh Steelers to Monday from Sunday.


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Please stop ignoring your flight attendants     
Please stop ignoring your flight attendants
\"I\'ve seen this happen throughout my career,\" said Nelson, who joined United as a flight attendant in the 1990s and said passengers, jolted by a high-profile incident, often return to their lackadaisical ways. \"The question is: Is it two weeks? Three? Maybe as much as six? There are short memories.\"


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Six held over plot to disrupt London Stock Exchange    
Six held over plot to disrupt London Stock Exchange
She said it was thanks to the \"determined efforts\" of the Met\'s public order crime team and colleagues in Merseyside that officers \"were able to identify, locate and arrest those we suspect to be involved in this plot\".


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'Every day I wake up and I have a mission': Representing Ukraine continues to motivate Elina Svitolina on and off the court    
'Every day I wake up and I have a mission': Representing Ukraine continues to motivate Elina Svitolina on and off the court
\"We don\'t want to put any numbers in front of us,\" Svitolina said. \"We\'re looking at it as just each year is important and try to prepare as best for it as possible. We are going to see year by year. And then we\'ll see what the future will bring.\"


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Thousands Of Demonstrators March For Palestine In Global Day Of Action    
Thousands Of Demonstrators March For Palestine In Global Day Of Action
By entering your email and clicking Sign Up, you\'re agreeing to let us send you customized marketing messages about us and our advertising partners. You are also agreeing to our Terms of Service and Privacy Policy.


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Dive into the enigmatic mind of Lions coach Dan Campbell    
Dive into the enigmatic mind of Lions coach Dan Campbell
You can practically see the belief that emanates from Campbell as he wends his way around the field -- cap tilted back on his head, whistle swinging from his neck -- wishing each of his players a good day. He gives off the vibe that he handpicked every guy on the roster, and that he wouldn\'t trade any one of them for anyone else in the league. \"He sets us on the right way,\" offensive coordinator Ben Johnson says, \"and we just follow.\" They\'re in this together, for however long it lasts and wherever it takes them, kneecaps and all.


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Opinion | What Nikki Haley — and I — Learned at a Segregation Academy    
Opinion | What Nikki Haley — and I — Learned at a Segregation Academy
The Times is committed to publishing a diversity of letters to the editor. We’d like to hear what you think about this or any of our articles. Here are some tips. And here’s our email: letters@nytimes.com.


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Opinion | Why This Could Be a Dangerous Year for the Iowa Caucuses    
Opinion | Why This Could Be a Dangerous Year for the Iowa Caucuses
As you can imagine, this is not a lighthearted game like, say, charades or Hungry Hungry Hippos. It is complicated and grinding, the rules shift, and victory is highly subjective, relying on the savvy of the players’ pre- and postgame spinning. And this election, with Donald Trump dominating the race as a quasi-incumbent cult-of-personality leader, the known unknowns are even knottier.


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Purina Rebuts TikTok Rumors About Pet Food Safety    
Purina Rebuts TikTok Rumors About Pet Food Safety
Purina, which is based in St. Louis and is a subsidiary of Nestlé, was responding to unsubstantiated accounts that were shared in TikTok videos that accumulated thousands of views, and in a public Facebook group with 62,000 members called Saving Pets One Pet @ A Time. Dogs were having seizures, vomiting and suffering from diarrhea, according to these accounts, and some were dying, after eating Purina Pro Plan food.


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As War Enters 100th Day, Netanyahu Vows to Keep Fighting in Gaza    
As War Enters 100th Day, Netanyahu Vows to Keep Fighting in Gaza
“We are continuing the war until the end — until total victory, until we achieve all of our goals,” Mr. Netanyahu declared in a televised news conference on Saturday night, saying that “eliminating Hamas, returning all of our hostages and ensuring that Gaza will never again constitute a threat to Israel” were the goals.


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Larry Hogan Backs Nikki Haley for G.O.P. Presidential Nomination    
Larry Hogan Backs Nikki Haley for G.O.P. Presidential Nomination
Maggie Astor covers politics for The New York Times, focusing on breaking news, policies, campaigns and how underrepresented or marginalized groups are affected by political systems. More about Maggie Astor


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‘Mean Girls’ Musical Triumphs at Box Office, With a TikTok Assist    
‘Mean Girls’ Musical Triumphs at Box Office, With a TikTok Assist
The news was a welcome reprieve for the theatrical box office, which did not benefit from a giant year-end blockbuster that often carries over into the new year. (Last year, during this weekend, “Avatar: The Way of Water” grossed an additional $40 million in its fifth weekend.) “Mean Girls” also offers confirmation that Paramount’s aggressive digital marketing strategies were successful.


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Defense Secretary Austin is 'actively involved and engaged' while hospitalized    
Defense Secretary Austin is 'actively involved and engaged' while hospitalized
Austin has been treated at Walter Reed National Military Medical Center since Jan. 1, following complications from a surgery nearly two weeks earlier to treat prostate cancer. Kirby said Sunday that physical therapy is part of the reason doctors have kept Austin in the hospital.


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Reaction: Vinicius sublime, Barcelona woeful as Real Madrid win Spanish Supercopa    
Reaction: Vinicius sublime, Barcelona woeful as Real Madrid win Spanish Supercopa
It will not be easy for Xavi to brush off the nature of this Clásico defeat. He credited last year\'s success in the competition as the catalyst for winning LaLiga. Barça are still alive in three other competitions -- LaLiga, the Champions League and the Copa del Rey -- but if things don\'t improve quickly, this loss may be looked back on as the catalyst for something entirely different in the coming months with his position under constant scrutiny. -- Sam Marsden


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U.S. and Iran Battle Through Proxies, Warily Avoiding Each Other    
U.S. and Iran Battle Through Proxies, Warily Avoiding Each Other
When Israel struck a suburb of Beirut on Jan. 2 to kill a Hamas leader, it mounted a very precise attack — exactly the opposite of its campaign in Gaza — to avoid harm to nearby Hezbollah fighters. That allowed Israeli officials to make clear to Hezbollah, the terrorist group funded and armed by Iran, that it had no interest in escalating the tit-for-tat strikes on Lebanon’s southern border. (Six days later it did kill Wissam Hassan Tawil, a commander of Hezbollah’s most elite force, the most senior Hezbollah officer killed thus far.)


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Four Dead and One Critically Hurt in Hot-Air Balloon Crash, Police Say    
Four Dead and One Critically Hurt in Hot-Air Balloon Crash, Police Say
Chief Gwaltney said investigators from the National Transportation Safety Board and the Federal Aviation Administration would likely examine, among other things, cellphone footage that might have been shot during the ride.


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Critics Choice Awards: Red Carpet Looks From Stars of Film and TV    
Critics Choice Awards: Red Carpet Looks From Stars of Film and TV
The Critics Choice Awards, hosted by Chelsea Handler on Sunday in Los Angeles, could be seen as a mere opening act to the Emmys on Monday. But because the awards recognize movies as well as television, film actors running full tilt at Academy Award nominations were unlikely to miss an opportunity for face time. (The next class of Oscar nominees will be announced on Jan. 23.)


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First look at the divisional round: Previewing Packers-49ers, plus lookaheads for other teams moving on    
First look at the divisional round: Previewing Packers-49ers, plus lookaheads for other teams moving on
Reason for divisional round optimism: How could it be anything besides quarterback C.J. Stroud after what we witnessed Saturday? When the proverbial lights were brightest, he delivered in a huge way against the Browns. His 98.4 QBR in that matchup was the best in the postseason since Josh Allen\'s dismantling of the Patriots two years ago. With Stroud playing this well, Houston suddenly has a higher upside than we perhaps ever realized. -- Walder


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Hit Men Are Easy to Find in the Movies. Real Life Is Another Story.    
Hit Men Are Easy to Find in the Movies. Real Life Is Another Story.
Jesse McKinley is a Metro correspondent for The Times, with an emphasis on coverage of upstate New York. He previously served as bureau chief in Albany and San Francisco, as well as stints as a feature writer, theater columnist and Broadway reporter for the Culture desk. More about Jesse McKinley


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Is seabed mining an economic necessity or a hazard?    
Is seabed mining an economic necessity or a hazard?
Mr Norton says that deep-sea mining needs \"strong environmental regulations\", but that the ISA also faces \"a balancing act\". \"What they need to do is really address the issue of the balance between risk and need.\"


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Tempers Flare as Guatemala’s Presidential Inauguration Is Delayed    
Tempers Flare as Guatemala’s Presidential Inauguration Is Delayed
Mr. Arévalo won Guatemala’s presidential election by a wide margin in August and has faced a barrage of legal attacks from prosecutors, judges and political leaders aimed at preventing him from taking office. On Sunday, he said that he and his running mate, Karin Herrera, would become president and vice president of Guatemala at 4 p.m. local time, according to Guatemalan law.


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How College-Educated Republicans Learned to Love Trump Again    
How College-Educated Republicans Learned to Love Trump Again
Then came Mr. Trump’s resurgence, in which he rallied every corner of the party, including the white working class. But few cross-sections of Republicans rebounded as much as college-educated conservatives, a review of state and national polls during the past 14 months shows.


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Opinion | A Strongman President? These Voters Crave It.    
Opinion | A Strongman President? These Voters Crave It.
Zeynep Tufekci (@zeynep) is a professor of sociology and public affairs at Princeton University, the author of “Twitter and Tear Gas: The Power and Fragility of Networked Protest” and a New York Times Opinion columnist. @zeynep • Facebook


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This Is the Average Social Security Benefit for Age 62    
This Is the Average Social Security Benefit for Age 62
The $21,756 Social Security bonus most retirees completely overlook If you\'re like most Americans, you\'re a few years (or more) behind on your retirement savings. But a handful of little-known \"Social Security secrets\" could help ensure a boost in your retirement income. For example: one easy trick could pay you as much as $21,756 more... each year! Once you learn how to maximize your Social Security benefits, we think you could retire confidently with the peace of mind we\'re all after. Simply click here to discover how to learn more about these strategies.


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Michigan St. walk-on Izzo nets first career points    
Michigan St. walk-on Izzo nets first career points
Michigan State (10-7, 2-4 Big Ten) countered 26 seconds later when Jaden Akins made a 3-pointer for a one-point lead. Mag gave Rutgers the lead with a lay-in with 14:13 left, but the advantage was short-lived as Hall threw down a dunk and followed with a three-point play to kick-start a 19-0 Michigan State outburst in a 4½-minute span.


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Spousal Social Security Benefits: 3 Things All Retired Couples Should Know    
Spousal Social Security Benefits: 3 Things All Retired Couples Should Know
The $21,756 Social Security bonus most retirees completely overlook If you\'re like most Americans, you\'re a few years (or more) behind on your retirement savings. But a handful of little-known \"Social Security secrets\" could help ensure a boost in your retirement income. For example: one easy trick could pay you as much as $21,756 more... each year! Once you learn how to maximize your Social Security benefits, we think you could retire confidently with the peace of mind we\'re all after. Simply click here to discover how to learn more about these strategies.


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Democrats Fret That Biden’s Power Players Are Not at His Campaign Base    
Democrats Fret That Biden’s Power Players Are Not at His Campaign Base
“We invite everyone concerned about the existential threat that Donald Trump and MAGA Republicans pose to our freedom and democracy to channel their energy toward organizing, donating and talking to their friends about the stakes of this election,” said Kevin Munoz, the spokesman.


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As it happened: Djokovic passes difficult first round test    
As it happened: Djokovic passes difficult first round test
The 2024 Australian Open tournament is underway! We\'re just two weeks away from crowning a men\'s and women\'s champion - can anyone dethrone the king of Melbourne Park, Novak Djokovic? What about on the women\'s side - will Aryna Sabalenka go back-to-back? Or can Naomi Osaka complete a dream return to the blue courts?


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This 1 Move Could Add Nearly $5 Billion to Amazon's Bottom Line in 2024, According to a Wall Street Analyst    
This 1 Move Could Add Nearly $5 Billion to Amazon's Bottom Line in 2024, According to a Wall Street Analyst
John Mackey, former CEO of Whole Foods Market, an Amazon subsidiary, is a member of The Motley Fool’s board of directors. Bank of America is an advertising partner of The Ascent, a Motley Fool company. Adam Levy has positions in Amazon, Netflix, and Walt Disney. The Motley Fool has positions in and recommends Amazon, Bank of America, Netflix, and Walt Disney. The Motley Fool has a disclosure policy.


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War or No War, Many Older Ukrainians Want to Stay Put    
War or No War, Many Older Ukrainians Want to Stay Put
Homes built with their own hands are now crumbling walls and blown-out windows, with framed photographs of loved ones living far away. Some people have already buried their children, and their only wish is to stay close so they can be buried next to them.


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House Republicans say they will re-subpoena Hunter Biden in coming weeks    
House Republicans say they will re-subpoena Hunter Biden in coming weeks
House Republicans have been investigating the president\'s son\'s foreign business dealings, claiming with little concrete evidence that President Joe Biden unlawfully benefitted from them. The Biden family and the White House have denied any allegations of wrongdoing.


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Opinion | This Is the Actual Danger Posed by D.E.I.    
Opinion | This Is the Actual Danger Posed by D.E.I.
To put it simply, the problem with D.E.I. isn’t with diversity, equity, or inclusion — all vital values. The danger posed by D.E.I. resides primarily not in these virtuous ends, but in the unconstitutional means chosen to advance them.


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Top diplomats meet in Davos on Ukraine 'peace formula'    
Top diplomats meet in Davos on Ukraine 'peace formula'
Nigeria\'s national security adviser Nuhu Ribadu could be seen attending the NSA meeting. Yermak said that there were participants from 18 Asian countries, 12 African countries and 6 South American countries.


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Biotech and pharma companies are betting on a promising class of cancer drugs to drive growth    
Biotech and pharma companies are betting on a promising class of cancer drugs to drive growth
Pfizer believes the Seagen acquisition will bring in more than $10 billion in risk-adjusted sales by 2030. Seagen specifically brings four approved cancer drugs, including three ADCs, which will beef up Pfizer\'s own ADC portfolio. 


Work


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Biotech and pharma companies are betting on a promising class of cancer drugs to drive growth    
Biotech and pharma companies are betting on a promising class of cancer drugs to drive growth
Pfizer believes the Seagen acquisition will bring in more than $10 billion in risk-adjusted sales by 2030. Seagen specifically brings four approved cancer drugs, including three ADCs, which will beef up Pfizer\'s own ADC portfolio. 


Work
'Every day I wake up and I have a mission': Representing Ukraine continues to motivate Elina Svitolina on and off the court    
'Every day I wake up and I have a mission': Representing Ukraine continues to motivate Elina Svitolina on and off the court
\"We don\'t want to put any numbers in front of us,\" Svitolina said. \"We\'re looking at it as just each year is important and try to prepare as best for it as possible. We are going to see year by year. And then we\'ll see what the future will bring.\"


Work
As it happened: Djokovic passes difficult first round test    
As it happened: Djokovic passes difficult first round test
The 2024 Australian Open tournament is underway! We\'re just two weeks away from crowning a men\'s and women\'s champion - can anyone dethrone the king of Melbourne Park, Novak Djokovic? What about on the women\'s side - will Aryna Sabalenka go back-to-back? Or can Naomi Osaka complete a dream return to the blue courts?


Work


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Scenes From a Harsh Winter Sweeping the U.S.    
Scenes From a Harsh Winter Sweeping the U.S.
Workers removed snow from Highmark Stadium in Orchard Park, N.Y., on Sunday. A potentially dangerous snowstorm that hit the Buffalo region on Saturday led the N.F.L. to push back the Bills wild-card playoff game against the Pittsburgh Steelers to Monday from Sunday.


Work
How, Where and When to Caucus in Iowa on Monday    
How, Where and When to Caucus in Iowa on Monday
After everyone has cast their secret ballots, workers at each caucus precinct will tally them up and report the total for each candidate to the state party. Results are typically available within a few hours.


Work
High School Principal Injured in Iowa School Shooting Has Died    
High School Principal Injured in Iowa School Shooting Has Died
In a statement posted on social media, the Perry Community School District described the principal as a “tremendous leader” and said, “Our school community is heartbroken by Dan’s death.”


Work
Four Dead and One Critically Hurt in Hot-Air Balloon Crash, Police Say    
Four Dead and One Critically Hurt in Hot-Air Balloon Crash, Police Say
Chief Gwaltney said investigators from the National Transportation Safety Board and the Federal Aviation Administration would likely examine, among other things, cellphone footage that might have been shot during the ride.


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Atlanta D.A. Defends Qualifications of Outside Lawyer She Hired for Trump Case    
Atlanta D.A. Defends Qualifications of Outside Lawyer She Hired for Trump Case
Instead, what Ms. Willis detailed were the frustrations and struggles that she said she has faced not only as a prosecutor, but also as a Black woman taking on the most powerful figure in the Republican Party.


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Democrats Fret That Biden’s Power Players Are Not at His Campaign Base    
Democrats Fret That Biden’s Power Players Are Not at His Campaign Base
“We invite everyone concerned about the existential threat that Donald Trump and MAGA Republicans pose to our freedom and democracy to channel their energy toward organizing, donating and talking to their friends about the stakes of this election,” said Kevin Munoz, the spokesman.


Work
Larry Hogan Backs Nikki Haley for G.O.P. Presidential Nomination    
Larry Hogan Backs Nikki Haley for G.O.P. Presidential Nomination
Maggie Astor covers politics for The New York Times, focusing on breaking news, policies, campaigns and how underrepresented or marginalized groups are affected by political systems. More about Maggie Astor


Work
Opinion | This Is the Actual Danger Posed by D.E.I.    
Opinion | This Is the Actual Danger Posed by D.E.I.
To put it simply, the problem with D.E.I. isn’t with diversity, equity, or inclusion — all vital values. The danger posed by D.E.I. resides primarily not in these virtuous ends, but in the unconstitutional means chosen to advance them.


Work
A Defiant Netanyahu Says No One Can Halt Israel's War To Crush Hamas, Including The World Court    
A Defiant Netanyahu Says No One Can Halt Israel's War To Crush Hamas, Including The World Court
By entering your email and clicking Sign Up, you\'re agreeing to let us send you customized marketing messages about us and our advertising partners. You are also agreeing to our Terms of Service and Privacy Policy.


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Israel's Siege On Gaza Reaches 100 Days    
Israel's Siege On Gaza Reaches 100 Days
By entering your email and clicking Sign Up, you\'re agreeing to let us send you customized marketing messages about us and our advertising partners. You are also agreeing to our Terms of Service and Privacy Policy.


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Trump Blasts Nikki Haley On MSNBC To Erode Support Among Democrats    
Trump Blasts Nikki Haley On MSNBC To Erode Support Among Democrats
By entering your email and clicking Sign Up, you\'re agreeing to let us send you customized marketing messages about us and our advertising partners. You are also agreeing to our Terms of Service and Privacy Policy.


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Former Maryland Gov. Larry Hogan Endorses Nikki Haley For President    
Former Maryland Gov. Larry Hogan Endorses Nikki Haley For President
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Principal Who Put Himself In 'Harm's Way' To Protect Students In Iowa School Shooting Dies    
Principal Who Put Himself In 'Harm's Way' To Protect Students In Iowa School Shooting Dies
By entering your email and clicking Sign Up, you\'re agreeing to let us send you customized marketing messages about us and our advertising partners. You are also agreeing to our Terms of Service and Privacy Policy.


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Bernie Sanders Explains How A 'Humiliated' Trump Could Destroy Democracy    
Bernie Sanders Explains How A 'Humiliated' Trump Could Destroy Democracy
By entering your email and clicking Sign Up, you\'re agreeing to let us send you customized marketing messages about us and our advertising partners. You are also agreeing to our Terms of Service and Privacy Policy.


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'Honeymooners' Actor Joyce Randolph Dead At 99    
'Honeymooners' Actor Joyce Randolph Dead At 99
By entering your email and clicking Sign Up, you\'re agreeing to let us send you customized marketing messages about us and our advertising partners. You are also agreeing to our Terms of Service and Privacy Policy.


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U.S. Accuses Texas Of Blocking Border Agents From Trying To Save Drowning Migrants    
U.S. Accuses Texas Of Blocking Border Agents From Trying To Save Drowning Migrants
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'All My Children' And 'Grown Ups' Star Alec Musser Dies At 50    
'All My Children' And 'Grown Ups' Star Alec Musser Dies At 50
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Mia Goth Kicked An Extra In Head Before Having Him Fired, Lawsuit Claims    
Mia Goth Kicked An Extra In Head Before Having Him Fired, Lawsuit Claims
By entering your email and clicking Sign Up, you\'re agreeing to let us send you customized marketing messages about us and our advertising partners. You are also agreeing to our Terms of Service and Privacy Policy.




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